what is THALASSEMIA?
It is a hereditary blood disorder in which your body form less hemoglobin and very few red blood cells, as compared to the normal healthy individual. Hemoglobin is a blood protein that carries oxygen to the cells of the body. Deficiency of hemoglobin causes anemia and leaving you fatigued. If you have mild symptoms of anemia you may not need to worry for treatment. If you have severed type of anemia, then you have to go for blood transfusions, regularly.
What are the Sign and symptoms of Thalassemia?
Sign and symptoms of thalassemia may include the following:
Sign and symptoms depend upon the severity and type of thalassemia. Alpha-thalassemia, Thalassemia intermedia, Cooley anemia are the common types of thalassemia. In the severe type of thalassemia, sign and symptoms appear as the baby born. While in the case of others, children develop symptoms within the first two years of life.
What are the Causes of thalassemia?
A mutation in DNA, that makes hemoglobin, cause thalassemia. This mutated gene pass through generations. Thalassemia disrupts the normal production of hemoglobin and RBCs.With less hemoglobin and few red blood cells, you develop anemia and feel fatigued all the time.
When to see a doctor?
If you notice continuous decline health of your child, with any symptom of thalassemia, visit your child’s specialist immediately.
What are the types of Thalassemia?
The severity of thalassemia depends upon the number of gene mutations.if you have the single gene mutation, you thalassemia isn’t severe. If these mutations involved a number of genes then, thalassemia is more severe. Hemoglobin molecules are composed of alpha and beta particle, the effect of mutations on these particles
Alpha-Thalassemia
There are four genes that are involved in the formation of the alpha-hemoglobin chain. You get two from each parent .if you inherit:
Thalassemia minor
There are two genes that make the beta hemoglobin chain. You get 1 from each of your parents. If you inherit
1 mutated gene, you may have the very mild sign and symptoms of thalassemia. This condition is called beta thalassemia or thalassemia minor.
2 mutated genes, this condition is called thalassemia major. Babies born with these 2 mutated genes are healthy often at the time of birth. But they develop sign and symptoms, moderate to severe in the first 2 years of life. A Milder form of thalassemia major is called thalassemia intermedia, with 2 mutated genes of beta hemoglobin chain.
Who is at risk to suffer from thalassemia?
Thalasemia is more common in some races as Italians, Greeks, and Africans and in Asians. Thalassemia is an inherited disorder which means it is passed from parents to their children.
How thalassemia can be diagnosed?
Thalassemia generally diagnosed at very early age. Children with thalassemia major, show sign and symptoms mostly first year of life. That may get worse if left unmanaged and can be life threatening. There are number of blood tests and evaluation for the diagnosis of thalassemia.
What is prognosis of thalassemia?
Patients with mild thalassemia can expect a normal life expectancy. Patients with moderate or severe form of thalassemia can have good survival but only with continues treatment. Heart disease with the iron overload is the main cause of death of patients of thalassemia. So its extremely important to control iron level. A bone marrow transplant is complete cure for thalassemia. Surgical procedures might be requiring for the skeletal deformities in the patients suffering from thalassemia.
What kind of care require for the patient of thalassemia?
If you suffer from thalassemia or a care taker of a thalassemia patient you need to follow the care plan for the patient. Frequent blood count test and iron level test must be done. Heart function tests and liver function tests should also performed annually. As frequent transfusions can higher the chances to get viral infections. So its necessary to check upon the liver as well.
Prevention
If you carry a thalassemia gene, you can prevent it. But you need counseling about thalassemia. When you think about having your children, first consult a genetic counselor. If you have thalassemia, you can fight with it. We’ll help you.
Treatment at Saher Homeo Clinic
Here, we treat every individual at the genetic level. Every individual seeks treatment on the basis of symptoms and health condition. We have a number of completely well managed cases.
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if urgent. Your personal case manager will ensure that you receive the best possible care.