Treatment of Pure Red Cell Aplasia in Homeopathy

  What IS PURE RED CELL APLASIA (PRCA)?

  Pure red cell aplasia is a very rare blood disorder in which the production of erythrocytes ceased due to the genetic mutation. It may occur in the patients that have a disease like tumors, systemic lupus erythematosus, thymomas, autoimmune diseases. PRCA has following three types usually.

What are the types of Pure red cell aplasia?

There are following types of pure red cell aplasia.

Congenital Pure Red Cell Aplasia:

This is also called diamond-blackfan anemia. It is usually diagnosed in the first two years of life, but in severe conditions, it may be diagnosed in first 2,3 months of life. Some children with pure red clel aplasia usually show signs and symptoms of malformation and some disabilities in mental level. Only several hundred children reported cases of congenital aplasia worldwide.

Acquired red cell aplasia:

This is a rare form of red cell aplasia in affecting adults. It is considered that acquired pure red cell aplasia is caused by any immune disorders, recurrent infections, certain medications and a tumor in the thymus gland.

Acute-self limiting pure red cell Aplasia:

This is a most common type of red cell aplasia caused by a certain drug or viral attack.most of the time when virus or medicine eliminate from the body, the PRCA also disappear. If you already have hemolytic anemia, then PRCA can be fatal for you. There is a difference in pure red cell aplasia and aplastic anemia. In aplastic anemia, all the RBCs, WBCs, and platelets become affected and in case of pure red cell aplasia only red blood cells line is affected, while the number of white blood cells and platelets remain in normal ranges.

Affected Populations

Acquired form of pure red cell aplasia is very rare and it affects males and females in equal proportions.

Relation of Pure red cell aplasia with Aplastic anemia:

There is a major difference between pure red cell aplasia and aplastic anemia. In pure red cell aplasia only red blood cells are affected. Whilst in aplastic anemia all the cells that bone marrow form get affected. They become lower in quantity.

What are the Sign and symptoms of pure red cell aplasia?

All patients of PRCA have anemia, its Sign and symptoms include:

• Fatigue
• Low count of red blood cells
• Dizziness
• Breathless
• Pale skin

Patients with Acquired PRCA may have other sign and symptoms too, due to the underlying disease.

When to visit a doctor?

If your child has paler complexion and showed sign and symptoms of anemia by birth, then immediately took him to the doctor. In acquired PRCA, patient experience this condition with other fatal health issues. It can be diagnosed with lab investigations, as the person visit the doctor.

What are the Causes of Pure red cell aplasia?

Mostly it is assumed that PRCA is caused by autoimmune disorders and mistaken attack of the body’s own immune cells on the blood-forming stem cells.

• Congenital
• Certain drugs
• Infections
• Autoimmune disease
• Idiopathic

How we can diagnose PRCA?

There are some tests that required for the diagnosis of pure red cell aplasia.

• Physical exam and history
• Blood tests:
  • A complete blood count with a differential that looks at the total number and type of blood cells in your blood
  • A reticulocyte count to determine blood levels of young red cells
  • A blood smear so your doctor can look at your blood under a microscope
• Bone marrow tests, which includes bone marrow aspiration and biopsy. With help of these tests doctors find out how bone marrow looks.

In such case patient should look a doctor who works on the bone marrow failures.

Life expectancy with PRCA

• Life expectancy with congenital pure red cell aplasia is limited.
• Patients having PRCA due to the idiopathic cause have a life expectancy of 1-2decades.
• The life span of the patients with Acquired PRCA depends upon the underlying disease.

What are the Risk factors?

Risk factors of PRCA include if you have :

• Thymomas (tumors of the thymus gland)
• Certain viruses like Parvovirus B-19
• Inherited genetic disorders
• Autoimmune diseases, like hepatitis, rheumatoid arthritis or having a clonal large population of lymphocytes that attack red blood cells precursors in the bone marrow.
• Treatment at Saher Homeo Clinic
• Here, at Saher Welfare Foundation, we treat every individual at the genetic level. Every individual seeks treatment on the basis of symptoms and health condition. we have a number of completely cured cases. See their stories here    
• Related Disorders
• There are some other blood disorders who’s symptoms may look similar to the pure red cells aplasia. They are thought for the differential diagnosis
• In Aplastic Anemia there is a complete failure of bone marrow to form blood cells including rbcs, wbcs and platelets. Some other types of anemia can cause red blood cells destruction. The reason for aplastic anemia is uncertain and sometimes it is unknown. It can be happen after a radiotherapy or toxic reaction to some chemicals. In some cases aplastic anemia can appear with the tumor of thymus gland.
• Another very rare Blackfan-Diamond Anemia is a genetic blood disorder in which patient suffer from blood deficiency after birth. With the blood cell abnormalities patient also suffer with paleness, lethargy, weakness and abnormal physical appearance.
• Fanconi’s Anemia is another rare form of aplastic anemia in which patient suffer with bone marrow abnormalities. They usually present with abnormally small size of head, pigmented skin, and abnormal functions of sex organs. Its complications may include infections such as meningitis, pneumonia, excessive bleeding and leukemia. Other malignancies can also occur.